Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists

Author(s): Antonios Katsianis, Emmanouil Petrou, Anna Kostopoulou, George Theodorakis.

Journal Name: Cardiovascular & Hematological Agents in Medicinal Chemistry

Volume 12 , Issue 1 , 2014

Abstract:

Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve replacement, venous thromboembolism, advanced renal failure and the elderly.

Keywords: Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.

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Article Details

VOLUME: 12
ISSUE: 1
Year: 2014
Page: [9 - 13]
Pages: 5
DOI: 10.2174/187152571201141201092129

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