Pleiotropic Effects of Statin in Therapy in Heart Failure: A Review

Author(s): Michele Correale , Silvia Abruzzese , Carmen A. Greco , Morena Concilio , Matteo Di Biase , Natale D. Brunetti .

Journal Name: Current Vascular Pharmacology

Volume 12 , Issue 6 , 2014

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Abstract:

Clinical trials demonstrated that statin therapy is associated with a significant reduction in cardiovascular morbidity and mortality when used for either primary or secondary prevention of cardiovascular events. Several studies have shown that statins, having an important effect in the prevention of acute coronary syndromes, are also able to prevent heart failure (HF) in patients with coronary artery disease. This review summarizes the experimental and clinical evidence regarding the role of statins in the management of HF.

Keywords: Statins, heart failure.

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Article Details

VOLUME: 12
ISSUE: 6
Year: 2014
Page: [873 - 884]
Pages: 12
DOI: 10.2174/1570161112999141127161508
Price: $58

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