Targeting anti-HER-2 therapy, trastuzumab, Lapatinib, T-DM1, and Pertuzumab is a standard
therapy for HER-2-overexpressing breast cancer. But there are less data available related to anti-HER-2
therapy in elderly patients because they have been consistently underrepresented in clinical trials. Anti-
HER-2 therapy among an elderly population was reviewed including approaches for making treatment
Keywords: Anti-HER2 therapy, breast cancer, HER-2/neu, elderly.
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