Current Gene Therapy

Ignacio Anegon
Director INSERM UMR 1064-Center for Research in Transplantation and Immunology
CHU de Nantes. 30, boulevard
Nantes
France

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Microfluidic Methods for Non-Viral Gene Delivery

Author(s): Wing-Fu Lai.

Abstract:

Microfluidics is a compelling technology that shows considerable promise in applications ranging from gene expression profiling to cell-based assays. Owing to its capacity to enable generation of single droplets and multiple droplet arrays with precisely controlled composition and a narrow size distribution, recently microfluidics has been exploited for delivery of genes. This article provides an overview of recent advances in microfluidic gene delivery, and speculates the prospects for further research. The objectives of this article are to illustrate the potential roles played by microfluidics in gene delivery research, and to shed new light on strategies to enhance the efficiency of gene therapy.

Keywords: Droplet, gene delivery, gene therapy, microfluidics, microfabrication.

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Article Details

VOLUME: 15
ISSUE: 1
Year: 2015
Page: [55 - 63]
Pages: 9
DOI: 10.2174/1566523214666141114213915
Price: $58