Glycosidase inhibitors are important compounds that can interfere with several biosynthetic processes including
N-linked glycosylation and the biosynthesis of several glycoproteins. Understanding the biogenesis of naturally occurring
glycosidase inhibitors would be a crucial step towards the chemical synthesis of analogues of choice. This review focuses
on the current knowledge regarding the biosynthesis of a series of polyhydroxylated saturated nitrogen heterocycles
including nojirimycin and swainsonine among others, with a potent biological activity as inhibitors of glycosidases and
Keywords: Biosynthesis, deoxynojirimycin, glycosidase inhibitors, nojirimycin, swainsonine.
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