Chiral Bifunctional Ferrocenylphosphines as New Catalysts for aza- Morita-Baylis-Hillman Reactions of N-Sulfonated Imines with Methyl Vinyl Ketone
A series of new chiral bifunctional Ferrocenylphosphines was designed, synthesized and applied for
the asymmetric aza-Morita-Baylis-Hillman reaction of N-sulfonated imines with methyl vinyl ketone (MVK).
The reaction proceeded under mild conditions to afford the desired aza-MBH adducts in moderate to high
yields with up to 56% ee value.
Keywords: aza-MBH adducts, aza-Morita-Baylis-Hillman reaction, chiral bifunctional ferrocenylphosphines, organocatalyst.
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