Indications, Implications and Applications of Renal Denervation. Have we Discovered Something new?
Cristiano de Oliveira Dietrich,
Fabio Martins Nardo Botelho,
Erlon Oliveira de Abreu-Silva.
Hyperactivity of sympathetic nervous system is one of the main mechanisms to play a role in the
pathophysiology of hypertension. Its high prevalence and the low rates of adequate blood pressure control with
pharmacological treatment brought interest to novel therapeutical strategies. Percutaneous renal sympathetic denervation
emerged as an effective and safe alternative to reduce blood pressure in patients with resistant hypertension. Other
potential indications to this procedure are heart failure, cases of insulin resistance, obesity, obstructive sleep apnea and
Keywords: Blood pressure, hypertension, percutaneous ablation, renal denervation, resistant hypertension, sympathetic
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