Dental Stem Cell in Tooth Development and Advances of Adult Dental Stem Cell in Regenerative Therapies

Author(s): Jiali Tan, Xin Xu, Jiong lin, Li Fan, Yuting Zheng, Wei Kuang.

Journal Name: Current Stem Cell Research & Therapy

Volume 10 , Issue 5 , 2015

Become EABM
Become Reviewer

Abstract:

Stem cell-based therapies are considered as a promising treatment for many clinical usage such as tooth regeneration, bone repairation, spinal cord injury, and so on. However, the ideal stem cell for stem cell-based therapy still remains to be elucidated. In the past decades, several types of stem cells have been isolated from teeth, including dental pulp stem cells (DPSCs), stem cells from human exfoliated deciduous teeth (SHED), periodontal ligament stem cells (PDLSCs), dental follicle progenitor stem cells (DFPCs) and stem cells from apical papilla (SCAP), which may be a good source for stem cell-based therapy in certain disease, especially when they origin from neural crest is considered. In this review, the specific characteristics and advantages of the adult dental stem cell population will be summarized and the molecular mechanisms of the differentiation of dental stem cell during tooth development will be also discussed.

Keywords: Cell differential, dental follicle progenitor cells (DFPCs), dental pulp stem cells (DPSCs), molecular mechanisms, periodontal ligament stem cells (PDLSCs), stem cells from human exfoliated deciduous teeth (SHED), stem cells from apical papilla (SCAP), tooth development.

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 10
ISSUE: 5
Year: 2015
Page: [375 - 383]
Pages: 9
DOI: 10.2174/1574888X09666141110150634
Price: $58

Article Metrics

PDF: 40
HTML: 1