Markers of Systemic Inflammation in Obstructive Sleep Apnea Syndrome

Author(s): Kostas Archontogeorgis, Evangelia Nena, Maria Xanthoudaki, Demosthenes Bouros.

Journal Name: Current Respiratory Medicine Reviews

Volume 12 , Issue 2 , 2016

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Graphical Abstract:


Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by recurrent episodes of upper airway obstruction resulting in oxygen desaturations and sleep disruption. OSAS is associated with an augmented risk for cardiovascular and cerebrovascular morbidity and mortality. Several mechanisms have been proposed to explain the association between OSAS and cardiovascular dysfunction. Low-grade systemic inflammation may contribute to the development of the cardiovascular and metabolic diseases associated with OSAS. The purpose of this review is to summarize current evidence on the association between OSAS and markers of systemic inflammation.

Keywords: Inflammation, inflammatory markers, obstructive sleep apnea syndrome.

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Article Details

Year: 2016
Page: [142 - 151]
Pages: 10
DOI: 10.2174/1573398X10666141105234647
Price: $58

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PDF: 11