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Immunity to Helminths and Novel Therapeutic Approaches
eISBN: 978-1-60805-985-0, 2014 ISBN: 978-1-60805-989-8 ISSN: 2543-215X (Print) ISSN: 1879-744X (Online)
Indexed in: EBSCO, Ulrich's Periodicals Directory.
This volume covers research on the interaction of major helminth parasites with the immune system. The main focus of the e-book is the ability of helminths to subvert host immune responses, on the one hand. On the other hand, the immunological armamentarium of the host against invading parasites is described also in the light of new findings on innate and adaptive immunity. These include the discovery of a new category of lymphocytes, innate lymphoid cells, and the role of T helper cels such as Th1, Th2 and Th3 cells, T regulatory (Treg) and Th17 cells in helminth diseases and inflammation. The balance between these two T cell subsets during the various stages of helminth diseases is also discussed. The book concludes with a review of new therapeutic approaches to combat helminth parasites (biotherapy, vaccines and natural products).
Immunity to Helminths and Novel Therapeutic Approaches provides updated information for medical students, clinicians and researchers in the fields of parasitology, applied immunology and novel drug delivery.
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Emilio Jirillo, Thea Magrone and Giuseppe Miragliotta
Department of Basic Medical Sciences Neuroscience and Sensory Organs University of Bari Bari (Italy).