Microwave-mediated Regiospecific Synthesis of Some Novel Annulated Spiro[indoline-3,1`-indolizin]-2-ones

Author(s): Abdullah S. Al-Bogami , Abdelaziz S. El-Ahl .

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 1 , 2015

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Abstract:

A library of hitherto unknown functionalized and annulated spiro[indoline-3,1`-indolizin]-2-one derivatives incorporating thiophene moiety has been synthesized under conventional and microwave irradiation conditions. The structures, regio and diastereoselectivity of the synthesized cycloadducts have been confirmed using different analytical and spectral tools.

Keywords: 2d NMR, microwave irradiation, regioselectivity, spiro[indoline-3, 1`-indolizin]-2-one derivatives.

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Article Details

VOLUME: 12
ISSUE: 1
Year: 2015
Page: [2 - 12]
Pages: 11
DOI: 10.2174/1570178611666141016215558

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