Platelets as Potential Link Between Diabetes and Alzheimer's Disease

Author(s): Voahanginirina Randriamboavonjy, Kateryna Sopova, Konstantinos Stellos, Christoph Laske.

Journal Name: Current Alzheimer Research

Volume 11 , Issue 9 , 2014

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Abstract:

Diabetes is a well-known risk factor for Alzheimer`s disease (AD) development in the elderly. The molecular link between diabetes and AD is still not completely understood. Recent evidence suggests that platelet activation observed in diabetes may contribute to AD development. The present review summarizes the common molecular mechanisms involved in the pathophysiology of diabetes and AD and suggests novel therapeutic targets for prevention of the onset or slowing the progression of this disease.

Keywords: Alzheimer's disease, diabetes, platelets, vascular dementia.

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Article Details

VOLUME: 11
ISSUE: 9
Year: 2014
Page: [862 - 868]
Pages: 7
DOI: 10.2174/156720501109141013115258
Price: $58

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