Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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Synthesis and Insecticidal Activity of Acylthiourea Derivatives from β-pinene

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Abstract:

4-isopropylcyclohexa-1, 3-dienecarboxylic acid (dehydrocumic acid) was prepared from β-pinene, and a series of acylthiourea derivatives was obtained. The structures of title compounds were characterized by FT-IR, NMR, and MS. The insecticidal activities against ostrinia furnacclis and bemisia tabaci were evaluated. The title compounds exhibited moderate larvicidal activity against ostrinia furnacclis. The preliminary study showed the introduction of orth and paro substitute displayed relatively good performance. The study promoted new application of β-pinene and its derivatives in pesticide management as botanical insecticide.

Keywords: Acylthiourea derivatives, β-pinene, botanical insecticide, insecticidal activity.

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Article Details

VOLUME: 12
ISSUE: 3
Year: 2015
Page: [241 - 249]
Pages: 9
DOI: 10.2174/1570180811666141009234615
Price: $58