Patents on Potential Drugs to Treat Alzheimer’s Disease: Special Emphasis on Small Peptides

Author(s): Pazhani Sundaram, Aravind K. Nambiar, Ranjini K. Sundaram.

Journal Name: Recent Patents on CNS Drug Discovery (Discontinued)

Volume 9 , Issue 2 , 2014

Abstract:

The primary objective of this article is to review patents and the related scientific work on naturally occurring compounds, heterocyclic compounds and small peptides that are being explored for their utility for the treatment of Alzheimer’s disease (AD). In this review, a special emphasis is given to the patents, including our patent issued in 2013, on peptides that bind to Aβ. Utility of the peptides that prevent aggregation or those that help in clearance of Aβ is discussed as the latter can be considered as an important arm in combination therapy for AD.

Keywords: Alzheimer’s disease, Alzheimer’s therapeutics, A-beta binders, patents, retro-inverse peptides.

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Article Details

VOLUME: 9
ISSUE: 2
Year: 2014
Page: [71 - 75]
Pages: 5
DOI: 10.2174/1574889809666140919123006
Price: $58

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