Current Proteomics

Bernd Rehm  
Institute of Molecular BioSciences Massey University
Private Bag 11222
Palmerston North
New Zealand

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Magnetite Nanostructures with Applications in Cancer Therapy

Author(s): Roxana Cristina Popescu, Alexandru Mihai Grumezescu.

Graphical Abstract:


Abstract:

Various biomedical applications that use Fe3O4 magnetic nanoparticles, both for diagnostic or/and therapy have been described. This review summarizes the most common synthesis methods for Fe3O4 nanoparticles, recently used for developing applications which improve the cancer treatment. We emphasize the tumor targeting possibilities for such systems, the magnetic hyperthermia and controlled delivery of anti-tumor, focusing on Fe3O4-based systems for osteosarcoma treatment using Doxorubicin as chemotherapeutic agent.

Keywords: Cancer therapy, drug delivery systems, Fe3O4, hyperthermia, magnetite, nanomedicine, targeting.

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Article Details

VOLUME: 11
ISSUE: 2
Year: 2014
Page: [128 - 138]
Pages: 11
DOI: 10.2174/157016461102140917122621
Price: $58