Current Nutrition & Food Science

Undurti N. Das  
UND Life Sciences
Shaker Heights
OH 44120


Effects of Beer and Lettuce (Lactuca Sativa) Consumption on Antioxidant Status in Healthy Volunteers: A Small-Scale Crossover Trial

Author(s): Elena Azzini, Federica Intorre, Eugenia Venneria, Maria Stella Foddai, Elisabetta Toti, Giovina Catasta, Mirella Nardini, Lara Palomba, Laura Rossi, Ombretta Marconi, Giuseppe Perretti, Paolo Fantozzi, Giuseppe Maiani.


Beer and wine are the most consumed ethanol-containing beverages worldwide and their impact on human health has been largely studied. A small-scale double-blind crossover trial was performed in order to evaluate the effects of simultaneous consumption of alcoholic/non-alcoholic beer and lettuce on plasma antioxidant status.

15 volunteers were divided into 4 groups and venous blood samples were collected at various delays from the ingestion of meal. The latter consisted of 500 ml beverage (alcoholic beer, non-alcoholic beer, non-alcoholic beer with added alcohol and water) and 100 g of fresh salad with 10 g of olive oil.

Results showed that total antioxidant status was significantly different between the alcoholic and non- alcoholic intake. Most of the antioxidant molecules such as carotenoids, vitamin A, E, and C were not altered by meal consumption. Beer phenolic compounds are not the same in alcoholic and non-alcoholic beer in terms of content, thus corresponding to different ingested doses and bioavailability. Lettuce phenolic compounds are bioavailable, even if the association between beer and lettuce did not imply a higher effect on antioxidant status.

In conclusion, our results showed a plausible influence of the different production process on bioactive compounds content in beer and the influence of food matrix on their bioavailability.

Keywords: Alcoholic beer, non-alcoholic beer, humans, antioxidant status, phenolic acids, whole meal.

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

Year: 2014
Page: [163 - 172]
Pages: 10
DOI: 10.2174/1573401310666140306003310
Price: $58