Hypertension and diabetes mellitus are closely associated, Cardiovascular complications and organ damages
are augmented in hypertensive patients with diabetes mellitus compared to those without diabetes mellitus. The important
common worsening factors in diabetes mellitus and essential hypertension are insulin resistance associated with
sympathoexcitation. We should consider that sympathoinhibition is a reasonable therapy for the hypertensive patients with
diabetes mellitus to prevent cardiovascular complications and organ damages, and that sympathoinhibition could be
contributes to improve the survival of the hypertensive patients with diabetes mellitus.
Keywords: Brain, diabetes mellitus, hypertension, insulin resistance, metabolic syndrome, sympathetic nerve activity.
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