Silica Bound Sulphonic Acid Functionalized Imidazolium Ionic Liquid as a Recyclable and Recoverable Catalyst for N-Boc Protection of Amines

Author(s): Amanpreet Kaur, Vasundhara Singh.

Journal Name:Current Catalysis

Volume 3 , Issue 3 , 2014

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Abstract:

In the present work, silica supported imidazolium based sulphonic acid was developed via a simple route as a hybrid organic-inorganic solid acid catalyst. The covalent anchoring to the silica support gave a stable catalyst in quantitative yield, while the ionic tag assisted in increasing the solubility of the reactants to facilitate the reaction under solventless conditions, being a homogeneous -heterogeneous catalytic system and having the distinct advantages of both. The catalytic efficacy of the solid acid catalyst was tested for the N-Boc protection of amines. The reactivity order followed by amines was aliphatic >aromatic> hetrocyclic>aminoalcohols. This efficient protocol has advantages of better workability of catalyst, reduced reaction time, improved yield, high TON and the catalyst is both recyclable and recoverable upto seven cycles.

Keywords: Amines, N-Boc protection, organic-inorganic hybrid catalyst, sulphonic acid catalyst.

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Article Details

VOLUME: 3
ISSUE: 3
Year: 2014
Page: [316 - 322]
Pages: 7
DOI: 10.2174/2211544703666140812232332
Price: $58