Anti-Obesity Drug Discovery and Development

Anti-Obesity Drug Discovery and Development

Volume: 2

Indexed in: EBSCO, Ulrich's Periodicals Directory

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric ...
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Natural Compounds – Anti-Obesity Properties

Pp. 211-241 (31)

Sara M. Reyna and Jameela Banu

Abstract

Obesity is a global epidemic with increasing number of individuals becoming overweight. World Health Organization (WHO) has called obesity a preventable disease mainly because most obese patients benefit by changing food habits and lifestyle. It is very well established that obesity increases the risk of several life threatening diseases like insulin resistance, diabetes, atherosclerotic vascular disease (CVD), cancer, chronic inflammation, bone disorders etc. Several natural products like herbs, dairy products, and products from marine organisms have been reported to have anti-obesity properties. These products reduce obesity by influencing different pathways such as decreasing intestinal absorption, fatty acid synthesis, adipocyte differentiation as well as increasing intestinal transit, beta oxidation, and metabolic rate. In this chapter, we have compiled information about the use of different natural products as anti-obesity agents and how they affect body weight.

Keywords:

Adipogenesis, animal products, fat metabolism, inflammation, multi compound mixtures, natural compounds, obesity, oxidative stress, plant products, toxicity.

Affiliation:

Coordinated Program in Dietetics and Department of Biology, University of Texas-Pan American, 1201, W University Dr., Edinburg, TX 78539-2999, USA.