Abstract
The experience of early adversity can increase one’s risk of psychopathology later in life. Extremely low birth weight (ELBW) provides a unique model of early adversity that affords us the opportunity to understand how prenatal and early postnatal stressors can affect the development of emotional, biological, and behavioural systems. Since the neuroendocrine system and emotion regulation can both be negatively affected by exposure to early adversity, and dysregulation in these regulatory systems has been linked to various forms of psychopathology, it is possible that these systems could mediate and/or moderate associations between early adversity, specifically ELBW, and later internalizing disorders. In this review, we discuss evidence of an early programming hypothesis underlying psychopathology and the identification of neuroendocrine markers of early adversity that may mediate/moderate the development of psychopathology.
Keywords: Cortisol, early adversity, early programming, emotion regulation, birth weight, internalizing disorders, neuroendocrine, psychopathology, stress.
Current Pediatric Reviews
Title:Early Adversity and Mental Health: Linking Extremely Low Birth Weight, Emotion Regulation, and Internalizing Disorders
Volume: 10 Issue: 3
Author(s): Jordana Waxman, Ryan J. Van Lieshout and Louis A. Schmidt
Affiliation:
Keywords: Cortisol, early adversity, early programming, emotion regulation, birth weight, internalizing disorders, neuroendocrine, psychopathology, stress.
Abstract: The experience of early adversity can increase one’s risk of psychopathology later in life. Extremely low birth weight (ELBW) provides a unique model of early adversity that affords us the opportunity to understand how prenatal and early postnatal stressors can affect the development of emotional, biological, and behavioural systems. Since the neuroendocrine system and emotion regulation can both be negatively affected by exposure to early adversity, and dysregulation in these regulatory systems has been linked to various forms of psychopathology, it is possible that these systems could mediate and/or moderate associations between early adversity, specifically ELBW, and later internalizing disorders. In this review, we discuss evidence of an early programming hypothesis underlying psychopathology and the identification of neuroendocrine markers of early adversity that may mediate/moderate the development of psychopathology.
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Cite this article as:
Waxman Jordana, Van Lieshout J. Ryan and Schmidt A. Louis, Early Adversity and Mental Health: Linking Extremely Low Birth Weight, Emotion Regulation, and Internalizing Disorders, Current Pediatric Reviews 2014; 10 (3) . https://dx.doi.org/10.2174/157339631003140722103523
DOI https://dx.doi.org/10.2174/157339631003140722103523 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
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