Infectious Disorders - Drug Targets

(Formerly Current Drug Targets - Infectious Disorders)

Jean-Marc Sabatier  
Laboratoire ERT 62 'Ingénierie des peptides à visée thérapeutique' 
Université de la Méditerranée
Faculté de Médecine Nord
Boulevard Pierre Dramard
13916 - MARSEILLE, Cedex 20
France

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Vaccination of Older Adults with Dementia Against Respiratory Infections

Author(s): Iman Ridda, Fereshteh Dastouri, Catherine King, Jiehui Kevin Yin, Mohamed Tashani, Harunor Rashid.

Abstract:

People with dementia are at a greater risk of complications from respiratory infections therefore can benefit from vaccinations against influenza, pneumococcal disease and pertussis. This review aimed to evaluate the uptake and impact of vaccination in older adults with dementia against respiratory infections and identify knowledge gaps. Key databases were explored, search results were assessed, relevant studies identified, and data were synthesised and summarised. Most available data suggest that older adults with dementia are less likely to receive influenza or pneumococcal vaccine while a few studies indicate an increase in vaccination uptake but poor immunogenicity. Among dementia patients, community dwellers have a lower vaccination rate than home care residents. However, vaccinations against influenza and pneumococcal disease can benefit individuals with dementia by reducing both mortality and morbidity. Health professionals caring for patients with dementia could play a role in fostering vaccination of these individuals.

Keywords: Cognitive impairment, dementia, immunisation, immunosenescence, vaccines.

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Article Details

VOLUME: 14
ISSUE: 2
Year: 2014
Page: [133 - 139]
Pages: 7
DOI: 10.2174/1871526514666140713153645
Price: $58