Bismuth nitrate-catalyzed microwave-assisted one-pot three components Aza-Diels-Alder reaction has been
investigated. This method has been used for an efficient synthesis of 2-azabicyclo[2,2,2] cyclooctanones.
Alkaloids, aza-Diels-Alder, azabicycle, bismuth nitrate, cycloadducts, diastereoselectivity, dienophile, endo/exo,
heterocycles, in situ, keto-enol tautomerization, Lewis acid, microwave chemistry, natural product, one-pot chemistry.
Department of Chemistry, The University of Texas Pan American, 1201 West University Drive, Edinburg, Texas 78539, USA.