Mini-Reviews in Medicinal Chemistry

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Benzocoumarins: Isolation, Synthesis, and Biological Activities

Author(s): Hai-Ning Lv, Peng-Fei Tu, Yong Jiang.

Abstract:

Benzocoumarins are coumarins with a phenyl group bonded to 3,4-, 5,6-, 6,7-, or 7,8-positions. Over the past years, significant efforts have been made not only to isolate the novel structural analogs of benzocoumarins with prominent bioactivities but also to design new synthetic methods to synthesize benzocoumarins with better or novel biological properties. The aim of this review is to provide the readers with an overview of the research progress of benzocoumarins from 1953 to May 2014, covering its isolation, synthesis, and biological activities.

Keywords: Benzocoumarins, biological activities, isolation, natural products, synthesis.

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Article Details

VOLUME: 14
ISSUE: 7
Year: 2014
Page: [603 - 622]
Pages: 20
DOI: 10.2174/1389557514666140622204608
Price: $58