Abstract
Benzocoumarins are coumarins with a phenyl group bonded to 3,4-, 5,6-, 6,7-, or 7,8-positions. Over the past years, significant efforts have been made not only to isolate the novel structural analogs of benzocoumarins with prominent bioactivities but also to design new synthetic methods to synthesize benzocoumarins with better or novel biological properties. The aim of this review is to provide the readers with an overview of the research progress of benzocoumarins from 1953 to May 2014, covering its isolation, synthesis, and biological activities.
Keywords: Benzocoumarins, biological activities, isolation, natural products, synthesis.
Mini-Reviews in Medicinal Chemistry
Title:Benzocoumarins: Isolation, Synthesis, and Biological Activities
Volume: 14 Issue: 7
Author(s): Hai-Ning Lv, Peng-Fei Tu and Yong Jiang
Affiliation:
Keywords: Benzocoumarins, biological activities, isolation, natural products, synthesis.
Abstract: Benzocoumarins are coumarins with a phenyl group bonded to 3,4-, 5,6-, 6,7-, or 7,8-positions. Over the past years, significant efforts have been made not only to isolate the novel structural analogs of benzocoumarins with prominent bioactivities but also to design new synthetic methods to synthesize benzocoumarins with better or novel biological properties. The aim of this review is to provide the readers with an overview of the research progress of benzocoumarins from 1953 to May 2014, covering its isolation, synthesis, and biological activities.
Export Options
About this article
Cite this article as:
Lv Hai-Ning, Tu Peng-Fei and Jiang Yong, Benzocoumarins: Isolation, Synthesis, and Biological Activities, Mini-Reviews in Medicinal Chemistry 2014; 14 (7) . https://dx.doi.org/10.2174/1389557514666140622204608
DOI https://dx.doi.org/10.2174/1389557514666140622204608 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Delivery of Intracellular-Acting Biologics in Pro-Apoptotic Therapies
Current Pharmaceutical Design Differences in Antiproliferative Activity Between Salinomycin-AZT Conjugates Obtained via ‘Click’ and Esterification Reactions
Medicinal Chemistry Genetic and Epigenetic Regulation of Phosphoinositide 3-kinase Isoforms
Current Pharmaceutical Design Acetylenic Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Strategies for the Assessment of Metabolic Profiles of Steroid Hormones in View of Diagnostics and Drug Monitoring: Analytical Problems and Challenges
Current Drug Metabolism Berberine Administration in Treatment of Colitis: A Review
Current Drug Targets Novel Anthraquinone Derivatives as Dual Inhibitors of Topoisomerase 2 and Casein Kinase 2: In Silico Studies, Synthesis and Biological Evaluation on Leukemic Cell Lines
Anti-Cancer Agents in Medicinal Chemistry Comparing the Interaction of Cyclophosphamide Monohydrate to Human Serum Albumin as Opposed to Holo-Transferrin by Spectroscopic and Molecular Modeling Methods: Evidence for Allocating the Binding Site
Protein & Peptide Letters Silencing GPX3 Expression Promotes Tumor Metastasis in Human Thyroid Cancer
Current Protein & Peptide Science The Epidemiology and Health Effects of Tobacco Smoke Exposure
Current Pediatric Reviews Pharmacometrics in Dose Finding or Dose Optimization of Anti-Retroviral and Anti-Tubercular Drugs
Infectious Disorders - Drug Targets Vitamin D and miRNAs in Cancer
Current Gene Therapy Anti-HER2 Cancer Therapy and Cardiotoxicity
Current Pharmaceutical Design The Effect of Quercetin on Doxorubicin Cytotoxicity in Human Breast Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry Influence of Resveratrol on Sphingolipid Metabolism in Hepatocellular Carcinoma Cells in Lipid Overload State
Anti-Cancer Agents in Medicinal Chemistry Mesalamine for Inflammatory Bowel Disease: Recent Reappraisals
Inflammation & Allergy - Drug Targets (Discontinued) Crude Methanol Extract of Rosin Gum Exhibits Specific Cytotoxicity against Human Breast Cancer Cells via Apoptosis Induction
Anti-Cancer Agents in Medicinal Chemistry Metabolism of Flavonoids in Human: A Comprehensive Review
Current Drug Metabolism Women Tipping the Scale During Pregnancy: A Special Population for Obesity Interventions,Treatments and Clinical Trials
Current Pharmaceutical Design Recent Clinical Experience with Oncolytic Viruses
Current Pharmaceutical Biotechnology