Synthetic Glycosylated Natural Products Have Satisfactory Activities

Author(s): Gangliang Huang, Xinya Mei.

Journal Name: Current Drug Targets

Volume 15 , Issue 8 , 2014

Become EABM
Become Reviewer

Graphical Abstract:


Many natural products contain sugar residues, which are essential components for great medicinal importance. The sugar moieties can improve water-solubility of natural products and decrease their toxicity. At the same time, the glycosidic residues are crucial for the activities of natural products. Much effort has been expended over the past decades in developing novel and efficient methodologies to synthesize the glycosylated natural products. This review highlights recent developments in the synthesis of glycosylated natural products. The structure-activity relationships of some of these glycosylated natural products, together with the structure characteristics of their interaction with the biological targets, are also involved.

Keywords: Activities, glycosylated natural products, recent development, total synthesis.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2014
Page: [780 - 784]
Pages: 5
DOI: 10.2174/1389450115666140617153348
Price: $58

Article Metrics

PDF: 25