Beta-lactamase and Carbapenemase Detection Methods: An Overview of Recent Patents
Meletis Georgios and Bagkeri Maria
Affiliation: St. Paul General Hospital of Thessaloniki, Greece.
Beta-lactam antibiotics constitute the agents most widely used against bacterial infections worldwide. Hence,
the emergence and spread of beta-lactam hydrolyzing enzymes among pathogenic bacteria has proved to be one of the major
medical issues especially when these enzymes inactivate carbapenems together with other beta-lactams. The prompt
detection of beta-lactamases is important for therapeutic and epidemiological purposes therefore, various appropriate
methodologies have been developed throughout the last decades. In the present overview, recent patents related to the detection
of beta-lactamases and especially of carbapenemases are discussed.
Keywords: Beta-lactamases, carbapenemases, patents.
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