Recent Patents on Anti-Infective Drug Discovery

Dieter Kabelitz  
Institute of Immunology
Universitätsklinikum Schleswig-Holstein
Campus Kiel
Arnold-Heller-Straße 3
Kiel, D-24105
Germany

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Beta-lactamase and Carbapenemase Detection Methods: An Overview of Recent Patents

Author(s): Meletis Georgios and Bagkeri Maria

Affiliation: St. Paul General Hospital of Thessaloniki, Greece.

Keywords: Beta-lactamases, carbapenemases, patents.

Abstract:

Beta-lactam antibiotics constitute the agents most widely used against bacterial infections worldwide. Hence, the emergence and spread of beta-lactam hydrolyzing enzymes among pathogenic bacteria has proved to be one of the major medical issues especially when these enzymes inactivate carbapenems together with other beta-lactams. The prompt detection of beta-lactamases is important for therapeutic and epidemiological purposes therefore, various appropriate methodologies have been developed throughout the last decades. In the present overview, recent patents related to the detection of beta-lactamases and especially of carbapenemases are discussed.

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Article Details

VOLUME: 9
ISSUE: 1
Page: [1 - 5]
Pages: 5
DOI: 10.2174/1574891X09666140608145307