Interactions of Native Cyclodextrins with Biorelevant Molecules in the Solid State: A Review

Author(s): Magdalena Ceborska.

Journal Name: Current Organic Chemistry

Volume 18 , Issue 14 , 2014

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Abstract:

Crystalline complexes of native cyclodextrins are of high interest due to their possible applications in various branches of industry. The encapsulation of active compounds by cyclodextrins results in a change of their properties, e.g. water solubility and bioavailability. Currently available native cyclodextrins inclusion complexes with biorelevant molecules in the solid state solved by X-ray crystallography are characterized. Studied guest compounds include aromas belonging to the family of terpenes and various drug molecules.

Keywords: Cyclodextrins, drugs, host-guest chemistry, inclusion complexes, solid state structures, terpenes.

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Article Details

VOLUME: 18
ISSUE: 14
Year: 2014
Page: [1878 - 1885]
Pages: 8
DOI: 10.2174/1385272819666140527232228
Price: $58

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