Recent Patents on Medical Imaging

Charles Bellows  
Chief Division of General Surgery
University of New Mexico
New Mexico


Coronary Intravascular Ultrasound (IVUS): Contemporary Applications and Bases for the Future

Author(s): Lucia Barbieri, Andrea Rognoni, Gioel G. Secco, Ettore Cassetti, Alon Schaffer, Gabriella Di Giovine, Maurizio Lazzero, Angelo S. Bongo, Paolo Marino, Giuseppe De Luca, Italo Porto and Alessandro Lupi

Affiliation: Department of Clinical and Experimental Medicine, University of Eastern Piedmont, “Maggiore della Carita” University Hospital, Cso Mazzini 18, 28100 Novara, Italy.


Despite the great innovations of non-invasive coronary imaging, coronary angiography still remains the gold standard for the assessment of coronary artery disease (CAD), even if with several limitations. In fact visual assessment of coronary stenosis is convenient and rapid, but often associated with large inter and intra-observer variability, above all in the setting of unstable CAD with complex lesions.

Coronary intravascular ultrasound (IVUS) allows accurate tomographic assessment of the coronary lumen and wall. IVUS has several diagnostic applications and is useful for choosing the most appropriate interventional strategy as well as for optimizing percutaneous coronary interventions (PCI) results. The present review focuses on: (1) the role of IVUS to guide therapeutic strategies in complex lesions requiring PCI, (2) IVUS capacity to interrogate borderline coronary stenoses, (3) new perspectives and recent patents for the future of IVUS technology.

Keywords: Coronary artery disease, intravascular ultrasound, IVUS, percutaneous coronary intervention, virtual histology IVUS.

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Article Details

Page: [6 - 15]
Pages: 10
DOI: 10.2174/2210684704666140526225738