Inflammation & Allergy-Drug Targets

(Formerly Current Drug Targets - Inflammation & Allergy)

Kurt S Zaenker
Institute of Immunology and Experimental Oncology
University Witten/Herdecke
Stockumerstraße 10
Witten, 58448


Brain-Skin Connection: Stress, Inflammation and Skin Aging

Author(s): Ying Chen Chen and John Lyga

Affiliation: Clinical Project Manager Global R&D Reckitt Benckiser One Philips Parkway Montvale, NJ 07645.


The intricate relationship between stress and skin conditions has been documented since ancient times. Recent clinical observations also link psychological stress to the onset or aggravation of multiple skin diseases. However, the exact underlying mechanisms have only been studied and partially revealed in the past 20 years or so. In this review, the authors will discuss the recent discoveries in the field of “Brain-Skin Connection”, summarizing findings from the overlapping fields of psychology, endocrinology, skin neurobiology, skin inflammation, immunology, and pharmacology.

Keywords: Inflammation, skin aging, stress response.

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Article Details

Page: [177 - 190]
Pages: 14
DOI: 10.2174/1871528113666140522104422