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Letters in Drug Design & Discovery
ISSN (Print): 1570-1808
ISSN (Online): 1875-628X
Epub Full Text Article
DOI: 10.2174/1570180811666140522002929      Price:  $95

Synthesis and Bioactivities of Novel 1, 3, 4-Oxadiazole Derivatives Containing Pyridine Moiety

Author(s): Guo-Xiang Sun, Yan-Xia Shi, Zhao-Hui Sun, Ming-Yan Yang, Hong-Ke Wu, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang
In this paper, some novel 1, 3, 4-oxadiazole derivatives containing 4-pyridyl group were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities, and the results indicated that some of the title compounds displayed good antifungal activities.
1, 3, 4-oxadiazole, pyridine, antifungal activity, microwave synthesis
College of Chemical Engineering Zhejiang University of Technology Hangzhou 310014 China.