Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety
Guo-Xiang Sun, Yan-Xia Shi, Zhao-Hui Sun, Ming-Yan Yang, Hong-Ke Wu, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang
Affiliation: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Keywords: 1, 3, 4-oxadiazole, antifungal activity, microwave synthesis, pyridine.
In this paper, some novel 1,3,4-oxadiazole derivatives containing 4-pyridyl group were synthesized under microwave
assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental
analyses. The target compounds were evaluated for their fungicidal activities, and the results indicated that some of the title
compounds displayed good antifungal activities.
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