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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety

Author(s): Guo-Xiang Sun, Yan-Xia Shi, Zhao-Hui Sun, Ming-Yan Yang, Hong-Ke Wu, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang

Volume 11, Issue 9, 2014

Page: [1119 - 1123] Pages: 5

DOI: 10.2174/1570180811666140522002929

Price: $65

Abstract

In this paper, some novel 1,3,4-oxadiazole derivatives containing 4-pyridyl group were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities, and the results indicated that some of the title compounds displayed good antifungal activities.

Keywords: 1, 3, 4-oxadiazole, antifungal activity, microwave synthesis, pyridine.

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