Letters in Drug Design & Discovery

Atta-ur-Rahman  , FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety

Author(s): Guo-Xiang Sun, Yan-Xia Shi, Zhao-Hui Sun, Ming-Yan Yang, Hong-Ke Wu, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang

Affiliation: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.

Keywords: 1, 3, 4-oxadiazole, antifungal activity, microwave synthesis, pyridine.

Graphical Abstract:


Abstract:

In this paper, some novel 1,3,4-oxadiazole derivatives containing 4-pyridyl group were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities, and the results indicated that some of the title compounds displayed good antifungal activities.

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Article Details

VOLUME: 11
ISSUE: 9
Page: [1119 - 1123]
Pages: 5
DOI: 10.2174/1570180811666140522002929