Nanoparticle-Delivered Quercetin for Cancer Therapy

Author(s): Ke Men, Xingmei Duan, Xia Wei Wei, Ma Ling Gou, Mei Juan Huang, Li Juan Chen, Zhi Yong Qian, Yu Quan Wei.

Journal Name:Anti-Cancer Agents in Medicinal Chemistry

Volume 14 , Issue 6 , 2014

Abstract:

Quercetin, a natural protective bioflavonoid, possesses diverse pharmacologic effects, such as antioxidant, anti-inflammatory, anti-proliferative, and anti-angiogenic activities. Recently, quercetin’s effect in cancer prevention and treatment was recognized. However, the poor water solubility and low-bioavailability of quercetin limit its clinical use in cancer therapy. Nanotechnology provides a method to create novel formulations for hydrophobic drug. Nanoparticles-delivered quercetin has attracted many attentions for its enhanced anticancer potential and promising clinical application. This review will discuss the application of nanotechnology in quercetin delivery for cancer therapy.

Keywords: Cancer therapy, nanoparticle, nanotechnology, quercetin.

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Article Details

VOLUME: 14
ISSUE: 6
Year: 2014
Page: [826 - 832]
Pages: 7
DOI: 10.2174/1871520614666140521122932
Price: $58