Garlic-Derived Allyl Sulfides in Cancer Therapy

Author(s): Hai-Xia Cao, Ke-Xiang Zhu, Jian-Gao Fan, Liang Qiao.

Journal Name:Anti-Cancer Agents in Medicinal Chemistry

Volume 14 , Issue 6 , 2014

Abstract:

Garlic (Allium sativam L.) is widely used in traditional herbal remedies and alternative medicine. The potential health benefits of garlic are largely attributed to its metabolic byproducts. Extensive in vivo and in vitro studies has demonstrated that the garlic derivatives possess anti-cancer effects, but the underlying mechanisms are not completely understood. In this mini-review, we aim to summarize the reported biological effects of garlic products as anti-tumor agents, and present the possible molecular mechanisms responsible for the anti-carcinogenesis effects of garlic and its derivatives.

Keywords: Allyl sulfides, apoptosis, carcinogenesis, cell cycle, Garlic, organosulfur compounds.

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Article Details

VOLUME: 14
ISSUE: 6
Year: 2014
Page: [793 - 799]
Pages: 7
DOI: 10.2174/1871520614666140521120811
Price: $58

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