Garlic-Derived Allyl Sulfides in Cancer Therapy
Garlic (Allium sativam L.) is widely used in traditional herbal remedies and alternative medicine. The potential health benefits
of garlic are largely attributed to its metabolic byproducts. Extensive in vivo and in vitro studies has demonstrated that the garlic
derivatives possess anti-cancer effects, but the underlying mechanisms are not completely understood. In this mini-review, we aim to
summarize the reported biological effects of garlic products as anti-tumor agents, and present the possible molecular mechanisms
responsible for the anti-carcinogenesis effects of garlic and its derivatives.
Keywords: Allyl sulfides, apoptosis, carcinogenesis, cell cycle, Garlic, organosulfur compounds.
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