Marine Toxin Structure Elucidation by Mass Spectrometry

Author(s): Pengyuan Liu.

Journal Name: Current Organic Chemistry

Volume 18 , Issue 7 , 2014

Become EABM
Become Reviewer

Graphical Abstract:


Mass spectrometry (MS) analysis plays an important role in the structural elucidation of natural marine toxins. In MS analysis, the chemical structural elucidation is mainly achieved by tandem MS (MS/MS) and multiple stage MS (MSn) techniques, in which fragmented product ions are used to interpret precursor ion structures. Herein we discuss the MS/MS and MSn behaviors of major marine toxins, such as domoic acid, anatoxins, saxitoxins, tetrodotoxins, okadaic acid, dinophysistoxins, azaspiracids, gymnodimines, spirolides, pinnatoxins, brevetoxins, ciguatoxins, yessotoxins, brevisulcenal-F, palytoxins, and protein/peptide toxins like conotoxins. In this review, our primal focus is on organization of literature data after 2000.

Keywords: Fragmentation pathway, marine toxin, mass spectrometry, multiple stages mass spectrometry, structural elucidation, tandem mass spectrometry.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2014
Page: [812 - 822]
Pages: 11
DOI: 10.2174/138527281807140515145401
Price: $58

Article Metrics

PDF: 12