At birth, GFR and tubular function of neonates is compromised as compared to older children and adults. These
functions are even less developed in premature infants. These facts have a direct bearing on drug dosing, fluid and electrolyte
administration, and maintenance of acid-base balance in neonates. Although many detailed methods of assessing renal
functions have been provided in this article, laboratory and radiologic studies available in most healthcare facilities are often
sufficient to provide a clinically relevant data in most patients, including neonates.
Keywords: Neonatal renal function, glomerular filtration rate, tubular functions, urinary concentration, renal tubular acidosis,
urine protein, microalbuminuria.
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