In recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable
attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the
hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors,
antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen
species and oxidative stress.
Keywords: Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.
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