The Natural Products Journal

Francesco Epifano  
Università "G. D'Annunzio"
Chieti-Pescara, Chieti Scalo (CH)
Italy

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Cannabinoids (CBD, CBDHQ and THC): Metabolism, Physiological Effects, Electron Transfer, Reactive Oxygen Species and Medical Use

Author(s): Peter Kovacic, Ratnasamy Somanathan.

Abstract:

In recent years, cannabinoids, particularly cannabidiol (medical marijuana), have attracted considerable attention. This review addresses various aspects including metabolism. Other cannabinols of interest are THC and the hydroxyl quinone metabolite. Physiological influences are addressed, particularly anticancer action, receptors, antioxidants, and neurological effects. A unifying mechanism is invoked based on electron transfer, reactive oxygen species and oxidative stress.

Keywords: Cannabinoids, cannabidiol, metabolism, therapy, toxicity, electron transfer, reactive oxygen species.

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2014
Page: [47 - 53]
Pages: 7
DOI: 10.2174/2210315504666140512220028