Current Physical Chemistry

Karl J. Jalkanen  
Gilead Sciences,Inc.
San Dimas, CA
USA

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Kinetics and Mechanism of Oxidation of Paracetamol by Thallic Perchlorate in Acid Medium

Author(s): Deepmala Pareek, Riya Sailani, Vinita K. Gupta, Chandra L. Khandelwal, Prem D. Sharma.

Abstract:

The kinetics and mechanism of oxidation of paracetamol (PCM) by thallium (III) in acid perchlorate medium has been studied.

The reaction exhibits first order kinetics with respect to the oxidant but a complex dependence of the substrate. The rate is reduced by an increase in the hydrogen ion concentration in a complex manner. A plausible reaction mechanism has been suggested to account for experimental observations.

Keywords: Kinetics, mechanism, oxidation, paracetamol, thallic perchlorate.

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Article Details

VOLUME: 4
ISSUE: 3
Year: 2014
Page: [302 - 309]
Pages: 8
DOI: 10.2174/1877946804666140429004357
Price: $58