Higher Efficiently Conversion of Heterocyclic Aryl Nitroalkenes to Ketones

Author(s): Dushu Huang, Jin-Gang Yu, Wei Liu, Yunhui Long, Jing Wang.

Journal Name:Current Organic Synthesis

Volume 11 , Issue 6 , 2014

Graphical Abstract:


Abstract:

Ketones were prepared by a modified Nef reaction using heterocyclic aryl nitroalkenes to react in a Fe-FeCl3-CH3COOH mixture with higher yield over 50% in sharp contrast with in Fe-HCl mixture with lower yield less than 30%, thus it’s cost-saving and relative environment friendly.

Keywords: Heterocyclic aryl nitroalkenes, Fe-FeCl3-CH3COOH system, ketones, Nef reaction, reductive hydrolysis.

Rights & PermissionsPrintExport

Article Details

VOLUME: 11
ISSUE: 6
Year: 2014
Page: [907 - 910]
Pages: 4
DOI: 10.2174/1570179411666140424232227
Price: $58