Abstract
This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.
Keywords: Antitumoral, asymmetric synthesis, catalysis, cycloaddition, metal, organocatalyst.
Current Topics in Medicinal Chemistry
Title:Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes
Volume: 14 Issue: 10
Author(s): Carmen Nejera and Jose M. Sansano
Affiliation:
Keywords: Antitumoral, asymmetric synthesis, catalysis, cycloaddition, metal, organocatalyst.
Abstract: This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.
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Cite this article as:
Nejera Carmen and Sansano M. Jose, Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes, Current Topics in Medicinal Chemistry 2014; 14 (10) . https://dx.doi.org/10.2174/1568026614666140423112145
DOI https://dx.doi.org/10.2174/1568026614666140423112145 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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