Enantioselective Synthesis in Carbohydrate-Based Drug Discovery: Imino Sugars, Alkaloids and Macrolide Antibiotics
Nuno M. Xavier,
Amélia P. Rauter.
This review is dedicated to enantioselective methods for the generation of carbohydrate-based lead compounds
for drug research. Selected examples encompassing imino sugars, bicyclic imino sugar-type alkaloids such as castanospermine,
swainsonine, or alexine, as well as macrolide glycosides are covered and discussed.
Keywords: Alkaloids, carbohydrates, enantioselective synthesis, imino sugars, macrolide glycosides.
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