Conformational Preferences of Chiral Acyclic Homooligomeric β2,2-Peptides
Jesus Hector Busto,
Jesus Manuel Peregrina,
Maria del Mar Zurbano.
α-Methylisoserine, a chiral acyclic quaternary β-amino acid, has been used to mimic secondary structures,
when it is incorporated in a homogeneous β2,2-dipeptide. In particular, the observed folded conformations in aqueous solution
can be regarded as mimics of β-turn.
Keywords: β-Peptides, conformational analysis, molecular dynamics, nuclear magnetic resonance.
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