Abstract
Compared with the conventional luminescent molecules, whose fluorescence is quenched once they aggregate, molecules with aggregation-induced emission (AIE) properties exhibit significantly enhanced emission in solid state or aggregates due to their unique molecular structures and stacking modes, showing potential applications in optoelectronic devices, biochemical sensors and bioimaging. Especially, AIE fluorophores recently have drawn much attention as an emerging sensory material. Taking advantage of AIE effects, fluorescence signals can be boosted by AIE dyes in presence of analytes, which offers a promising platform for sensor with intense fluorescence signal. In this review, we highlight the recent advances in the development of AIE fluorescent probes that are classified into various categories, including tetraphenylethenes, siloles, 9,10-distyrylanthracene, cyanostilbene and systems with extended π-conjugations to those even without typical AIE chromophores. The fluorescent behaviors of these probes toward different analyte are discussed.
Keywords: Aggregation-induced emission (AIE), bioimaging, biological probes, chemical sensors, fluorescence enhancement, fluorescent silica nanoparticles (FSNPs), restriction of intramolecular rotation (RIR).
Current Organic Chemistry
Title:Application of Aggregation-Induced Emission (AIE) Systems in Sensing and Bioimaging
Volume: 18 Issue: 8
Author(s): Lingyun Wang, Lingling Yang and Derong Cao
Affiliation:
Keywords: Aggregation-induced emission (AIE), bioimaging, biological probes, chemical sensors, fluorescence enhancement, fluorescent silica nanoparticles (FSNPs), restriction of intramolecular rotation (RIR).
Abstract: Compared with the conventional luminescent molecules, whose fluorescence is quenched once they aggregate, molecules with aggregation-induced emission (AIE) properties exhibit significantly enhanced emission in solid state or aggregates due to their unique molecular structures and stacking modes, showing potential applications in optoelectronic devices, biochemical sensors and bioimaging. Especially, AIE fluorophores recently have drawn much attention as an emerging sensory material. Taking advantage of AIE effects, fluorescence signals can be boosted by AIE dyes in presence of analytes, which offers a promising platform for sensor with intense fluorescence signal. In this review, we highlight the recent advances in the development of AIE fluorescent probes that are classified into various categories, including tetraphenylethenes, siloles, 9,10-distyrylanthracene, cyanostilbene and systems with extended π-conjugations to those even without typical AIE chromophores. The fluorescent behaviors of these probes toward different analyte are discussed.
Export Options
About this article
Cite this article as:
Wang Lingyun, Yang Lingling and Cao Derong, Application of Aggregation-Induced Emission (AIE) Systems in Sensing and Bioimaging, Current Organic Chemistry 2014; 18 (8) . https://dx.doi.org/10.2174/1385272819666140407214006
DOI https://dx.doi.org/10.2174/1385272819666140407214006 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Determination of Human Serum α1-Acid Glycoprotein and Albumin Binding of Various Marketed and Preclinical Kinase Inhibitors
Current Medicinal Chemistry Recent Patents on Anti-Cancer Potential of Helenalin
Recent Patents on Anti-Cancer Drug Discovery Recent Developments in CE-MS Based Metabolomics
Current Analytical Chemistry Synthesis of 2,4,6-Trichlorophenyl Hydrazones and their Inhibitory Potential Against Glycation of Protein
Medicinal Chemistry Protein Homeostasis as a Therapeutic Target for Diseases of Protein Conformation
Current Topics in Medicinal Chemistry QSAR of Chalcones Utilizing Theoretical Molecular Descriptors
Current Computer-Aided Drug Design Progress of Stimuli-Responsive Nanoscale Metal Organic Frameworks as Controlled Drug Delivery Systems
Current Drug Delivery Effects of Endocrine Disruptors on Developmental and Reproductive Functions
Current Drug Targets - Immune, Endocrine & Metabolic Disorders Magnetic Resonance-Based Metabolomics for Understanding Neurological Disorders: Current Status and Statistical Considerations
Current Metabolomics The Chemical Composition of Essential Oil of Warionea saharae Benth & Coss.(Fam.Asteraceae) from Southern Algeria
Current Bioactive Compounds Comprehensive Analysis of the mRNA-lncRNA Co-expression Profile and ceRNA Networks Patterns in Chronic Hepatitis B
Current Genomics Subtype Classification by Polymerase and Gag Genes of HIV-1 Iranian Sequences Registered in the NCBI GenBank
Current Proteomics Synthetic Exploitation of Halogenated Alkenes Containing EWG: Polysubstituted Sulfanyl Dinitro Butadienes from Sequential Nucleophilic Substitutions
Current Organic Synthesis Dietary Assumption of Plant Polyphenols and Prevention of Allergy
Current Pharmaceutical Design Cytotoxicity of Novel Sulfanilamides Towards Sensitive and Multidrugresistant Leukemia Cells
Current Medicinal Chemistry The Impetus of COVID -19 in Multiple Organ Affliction Apart from Respiratory Infection: Pathogenesis, Diagnostic Measures and Current Treatment Strategy
Infectious Disorders - Drug Targets Transient Receptor Potential Channels - Emerging Novel Drug Targets for the Treatment of Pain
Current Medicinal Chemistry Ceramidases in Hematological Malignancies: Senseless or Neglected Target?
Anti-Cancer Agents in Medicinal Chemistry A Review on Colorimetric Sensing of Tumor Markers Based on Enzyme-Mimicking Nanomaterials
Current Medicinal Chemistry Potential Use of Protease Inhibitors as Vaginal and Colorectal Microbicides
Current HIV Research