Depression is a common mental health issue worldwide leading to disability, functional decline and increased
mortality. Novel antidepressants have been developed during the last decades in order to treat depression syndromes.
Some evidence suggests that major depression has been associated with the development of congestive heart failure and
with adverse outcomes in patients with coronary heart disease. The purpose of the present article is to review the impact
of novel antidepressant patent drugs on cardiovascular disease and arterial hypertension.
Keywords: Arterial hypertension, bupropion, cardiovascular disease, depression, fluoxetine, norepinephrine reuptake inhibitors,
serotonin reuptake inhibitors.
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