Recent Developments on Thiourea Based Anticancer Chemotherapeutics
Swapandeep Singh Chimni.
The recent emergence of anticancer activity of thiourea derivatives have inspired the medicinal chemist to
design and synthesize new thiourea derivatives. These thiourea based anticancer chemotherapeutics inhibit cancer
propagation by acting as inhibitors of topoisomerase, protein tyrosine kinase, somatostatin agonists, sirtuins, and
carbonic anhydrase (CA). This review summarizes the recent developments on the thiourea based anticancer
Keywords: Anticancer chemotherapeutics, carbonic anhydrase (CA) inhibitors, protein tyrosine kinase inhibitors, sirtuins inhibitors, thiourea,
somatostatin agonists, topoisomerase inhibitors.
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