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Letters in Organic Chemistry
ISSN (Print): 1570-1786
ISSN (Online): 1875-6255
VOLUME: 11
ISSUE: 8
DOI: 10.2174/1570178611999140404111411      Price:  $58









Mechanically Activated Solid-State Synthesis of Phenylhydrazone Derivatives via High-Speed Ball Milling

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Author(s): Xingyi Zhu, Yuanyuan Chen, Yuhe Chen, Jue Wang and Weike Su
Pages 621-626 (6)
Abstract:
A series of phenylhydrazone derivatives was synthesized from arenediazonium tetrafluoroborates and active methylene compounds under high-speed ball milling. The reaction occurred in the absence of the solvent and products were obtained in good yield within short reaction times (no more than 30 min).
Graphical Abstract:
Keywords:
Ball milling, solid-state synthesis, phenylhydrazones, arenediazonium tetrafluoroborates, active methylene compounds.
Affiliation:
Key Laboratory of Pharmaceutical Engineering (Ministry of Education), Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, P.R. China.