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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Author(s): Rajesh O. Bora, Bashir Dar, Vidya Pradhan and Mazahar Farooqui

Volume 14, Issue 4, 2014

Page: [355 - 369] Pages: 15

DOI: 10.2174/1389557514666140329200745

Price: $65

Abstract

In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.

Keywords: Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.


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