[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications
Rajesh O. Bora, Bashir Dar, Vidya Pradhan and Mazahar Farooqui
Affiliation: Post Graduate and Research centre, Maulana Azad College, Aurangabad, and Indian Institute of Integrative Medicine Jammu 180001.
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles
have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic,
antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel
heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.
Keywords: Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles,
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