The increased interest in nanotechnology has resulted in an intense investigation and development of nanofabrication
methods. Among the bottom-up approaches, electro-spinning has attracted great interest in recent years. The
popularity of electro-spinning lays on the fact that it is a relatively simple and economic technique that enables production
of large quantities of nano- to micro-meter range fibrous materials with various morphologies and architectural features.
The versatility of electro-spinning is evidenced by the range of applications being utilised, including filtration, textiles,
batteries, and tissue engineering and regenerative medicine. Specifically to biomedical applications, advancements in the
electro-spinning setup have allowed the development of electro-spun mats that closely imitate native extracellular matrix
assemblies and provide opportunities for localised and sustained delivery of therapeutics. Herein, we are discussing different
electro-spinning setups and their distinct benefits for regenerative medicine applications.
Keywords: Architectural features, delivery of therapeutics/biologics, electro-spinning, nano- and micro-fibres, scaffold architecture,
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