The Multifaceted Potential of Electro-spinning in Regenerative Medicine
Kieran Fuller, Abhay Pandit and Dimitrios I. Zeugolis
Affiliation: Network of Excellence for Functional Biomaterials (NFB), National University of Ireland Galway (NUI Galway), Galway, Ireland.
The increased interest in nanotechnology has resulted in an intense investigation and development of nanofabrication
methods. Among the bottom-up approaches, electro-spinning has attracted great interest in recent years. The
popularity of electro-spinning lays on the fact that it is a relatively simple and economic technique that enables production
of large quantities of nano- to micro-meter range fibrous materials with various morphologies and architectural features.
The versatility of electro-spinning is evidenced by the range of applications being utilised, including filtration, textiles,
batteries, and tissue engineering and regenerative medicine. Specifically to biomedical applications, advancements in the
electro-spinning setup have allowed the development of electro-spun mats that closely imitate native extracellular matrix
assemblies and provide opportunities for localised and sustained delivery of therapeutics. Herein, we are discussing different
electro-spinning setups and their distinct benefits for regenerative medicine applications.
Keywords: Architectural features, delivery of therapeutics/biologics, electro-spinning, nano- and micro-fibres, scaffold architecture,
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