In Vitro Effects of Various Plants Extracts on the Growth of Trichomonas vaginalis
Seyedeh M. Sharafi, Morteza Yousefi, Hossein A. Yousefi, Gholamreza Asghari and Hossein Yousofi Darani
Affiliation: Department of Medical Parasitology and Mycology, Isfahan University of Medical Sciences, Isfahan, Iran.
Trichomoniasis is a common sexually transmitted disease (STD) caused by a protozoan parasite called Trichomonas
vaginalis. This disease, with roughly 170 million new infected people worldwide per year, is associated with various
problems such as pre-term delivery, high infant mortality or low birth weight. In addition, trichomoniasis increases
patient susceptibility to HIV infection. The mainstay medication for trichomoniasis is metronidazole, but some resistant
strains to this treatment have been identified. Moreover, treatment with metronidazole is associated with numerous side
effects. Thus efforts to identify new alternative drugs in order to control trichomoniasis are vital. The use of medicinal
herbs has gained widespread acceptance in both developing and non-developing societies because of owing to fewer side
effects and better patient tolerance. In our search for alternative drugs in the treatment of trichomoniasis, we reviewed the
effect of different plant extracts on Trichomonas vaginalis in vitro.
Keywords: Drug, plant, drug resistance, HIV infection, sexually transmitted diseases, trichomonas vaginalis.
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